Nasal congestion

Treatment of nasal congestion
Sodium chloride
Sodium chloride 0.9% nasal drops

Instil 1-2 drops into each nostril when necessary.

Xylometazoline
Xylometazoline 0.1% nasal drops

2–3 drops 2–3 times a day as required for maximum duration of 5 days, 0.1% solution to be administered into each nostril.

Xylometazoline 0.1% nasal spray

1 spray 1–3 times a day as required for maximum duration of 5 days, to be administered into each nostril.

Prescribing Notes:

  • Inhalation of warm moist air is useful in the treatment of symptoms of acute infective conditions. The addition of menthol or eucalyptus oil may improve the efficacy of the inhalation.
  • Sodium chloride 0.9% nasal drops may relieve nasal congestion by helping to liquefy nasal mucous secretions.
  • Topical nasal decongestants are of limited value because they can give rise to rebound congestion on withdrawal. 
  • Nasal decongestant sprays or drops containing xylometazoline hydrochloride, refer to: MHRA Drug Safety Update. Reminder these products should not be used for more than 5 days. 
  • Intranasal sodium chloride is a safe choice for pregnant women.

History Notes

09/09/2026

MHRA Drug Safety Update, ERWG May 26.

15/06/2022

East Region Formulary content agreed.

Pharmacy First - Nasal congestion

Topical nasal decongestant

Sodium chloride
Sodium chloride 0.9% nasal drops

Dose according to age and product licence.

Xylometazoline
Xylometazoline 0.05% nasal drops

Dose according to age and product licence.

Xylometazoline 0.1% nasal drops

Dose according to age and product licence.

Xylometazoline 0.1% nasal spray

Dose according to age and product licence.

Prescribing Notes:

  • Inhalation of warm moist air may give symptomatic relief.
  • Sodium chloride 0.9% nasal drops can relieve nasal congestion by helping liquefy nasal secretion and may be particularly helpful in infants.
  • Intranasal sodium chloride is a safe choice for pregnant women.
  • Topical nasal decongestants can give immediate relief but should be used short term as they can give rise to rebound congestion on withdrawal.
  • Nasal decongestant sprays or drops containing xylometazoline hydrochloride, refer to: MHRA Drug Safety Update. Reminder these products should not be used for more than 5 days. 
  • The CHM/MHRA has stated that non-prescription cough and cold medicines containing xylometazoline can be considered for up to 5 days’ treatment in children aged 6-12 years after basic principles of best care have been tried; these medicines should not be used in children under 6 years.

When to advise patient to contact GP
Patients with uncontrolled hypertension.

History Notes

09/09/2026

Prescribing information updated ERWG May and July 26

28/09/2023

Mandanol 0.9% nasal drops added in line with latest Pharmacy First list.

17/12/2021

Xylometazoline replaces pseudoephedrine to align to 01/10/2021 NHS Pharmacy First Scotland - Approved List of Products.

27/10/2020

Content migrated from ‘East Region Formulary: Pharmacy First - supporting minor ailments’ document.