Bronchiectasis
Treatment with mucolytics
Acetylcysteine
Acetylcysteine 600mg effervescent tablets sugar free
Carbocisteine
Carbocisteine 375mg capsules
Prescribing Notes:
- A trial of mucolytics can be considered in patients with bronchiectasis who have difficulty in sputum expectoration. The trial period should be advised by specialist. The patient should be reviewed and treatment discontinued if no clinical benefit observed.
- Ensure the most cost-effective brand of acetylcisteine is chosen in line with individual health Board preference.
- The dose of carbocisteine can be reduced as the condition improves.
History Notes
15/04/2026
Regional formulary chapter launched.
Treatment with nebulised saline
Sodium chloride
Sodium chloride 0.9% inhalation solution 2.5ml vials
Sodium chloride 0.9% nebuliser liquid 2.5ml unit dose ampoules
Sodium chloride 3% inhalation solution 4ml ampoules
Sodium chloride 3% inhalation solution 4ml vials
Sodium chloride 6% inhalation solution 4ml ampoules
Sodium chloride 6% inhalation solution 4ml vials
Sodium chloride 7% inhalation solution 4ml vials
Sodium chloride 7% nebuliser liquid 10ml bottles
Sodium chloride 7% nebuliser liquid 20ml vials
Sodium chloride 7% nebuliser liquid 30ml bottles
Sodium chloride 7% nebuliser liquid 5ml ampoules
Sodium chloride 7% nebuliser liquid 5ml bottles
History Notes
15/04/2026
Regional formulary chapter launched.
Prophylaxis of exacerbations of bronchiectasis
Specialist recommendation following investigations in secondary care.
Azithromycin
Azithromycin 250mg tablets
Prescribing Notes:
- Prescribing of azithromycin should be on the advice of a respiratory specialist, following sensitivities and investigations in secondary care.
- The use of azithromycin is for both its antibiotic and anti-inflammatory properties.
- Azithromycin should not be prescribed to patients who are currently smoking.
History Notes
15/04/2026
Regional formulary chapter launched.