Diverticulitis
The regional formulary will not cover all eventualities for infections medicines choices. As with any condition; patient specific factors and sensitivities need to be considered. Please consider this regional formulary advice alongside any relevant local Board guidelines.
Uncomplicated diverticulitis
No antibiotic treatment, if systemically well.
If systemically unwell, immunocompromised or significant comorbidity.
Co-trimoxazole
Co-trimoxazole 80mg/400mg tablets
960mg every 12 hours for 5 days.
Metronidazole
Metronidazole 400mg tablets
400mg every 8 hours for 5 days.
Prescribing Notes:
- Current guidelines advising the use of antibiotics in uncomplicated diverticulitis are not evidence based. In the majority of patients with mild diverticulitis, antibiotics are not required.
- Co-trimoxazole 80mg/400mg tablets are more cost-effective dose for dose than 160mg/800mg tablets.
History Notes
30/07/2026
Regional formulary chapter launched.