Parotitis

The regional formulary will not cover all eventualities for infections medicines choices. As with any condition; patient specific factors and sensitivities need to be considered. Please consider this regional formulary advice alongside any relevant local Board guidelines.

Treatment of parotitis

Consider mumps or other non-infective causes as a diagnosis.

If there are no signs of sepsis.


Flucloxacillin
Flucloxacillin 500mg capsules

500mg every 6 hours for 7 days.

Metronidazole
Metronidazole 400mg tablets

400mg every 8 hours for 7 days.

If penicillin allergic, or previous MRSA infection.


Doxycycline
Doxycycline 100mg capsules

100mg every 12 hours for 7 days.

Metronidazole
Metronidazole 400mg tablets

400mg every 8 hours for 7 days.

Prescribing Notes:

  • Most cases of bacterial parotitis are in frail elderly patients with dehydration.
  • Patients with persistent (>2weeks) symptoms or unexplained parotid swelling or suspected parotid duct calculi should be referred to ENT.

History Notes

30/07/2026

Regional formulary chapter launched.