Oral candidiasis
The regional formulary will not cover all eventualities for infections medicines choices. As with any condition; patient specific factors and sensitivities need to be considered. Please consider this regional formulary advice alongside any relevant local Board guidelines.
100,000units every 6 hours usually for 7 days and continued until 2 days after symptoms resolve.
2.5ml every 6 hours should be continued for at least 7 days after symptoms resolve.
For extensive severe infection or immunosuppressed patients.
Initially 200-400mg for 1 dose, to be given on first day, then 100-200mg once daily for 7-21 days (duration may be increased in severely immunocompromised patients).
Initially 200-400mg for 1 dose, to be given on first day, then 100-200mg once daily for 7-21 days (duration may be increased in severely immunocompromised patients).
Initially 200-400mg for 1 dose, to be given on first day, then 100-200mg once daily for 7-21 days (duration may be increased in severely immunocompromised patients).
Prescribing Notes:
- Diagnosis of oral candidiasis is usually made by identifying clinical features and excluding other differential diagnoses (see NICE CKS). Swabs to detect C. albicans, or antibody serology, are not thought to be diagnostically helpful as candidal organisms are a normal commensal found in many healthy people.
- Swabs should only be taken if thrush is clinically suspected and there has been a failure to respond to treatment.
- In unexplained oral candidiasis HIV testing should be offered.
- Consider use of spacer device, rinse mouth and clean teeth if oral thrush is related to inhaled corticosteroids.
- For miconazole gel, dental prostheses and orthodontic appliances should be removed at night and brushed with gel.
History Notes
30/07/2026
Regional formulary chapter launched.