Cardiovascular conditions in specialist settings

Specialist use medicines in Critical Care
Esmolol
Esmolol 100mg/10ml solution for injection vials

On specialist advice.

Levosimendan
Levosimendan 12.5mg/5ml solution for infusion vials

On specialist advice.

Nicardipine
Nicardipine 10mg/10ml solution for infusion ampoules

On specialist advice.

Nimodipine
Nimodipine 10mg/50ml solution for infusion vials

On specialist advice.

Adrenaline
Adrenaline (base) 10mg/10ml (1 in 1,000) solution for injection ampoules

On specialist advice.

Adrenaline (base) 1mg/10ml (1 in 10,000) dilute solution for injection pre-filled syringes

On specialist advice.

Dobutamine
Dobutamine 250mg/20ml solution for infusion ampoules

On specialist advice.

Dopamine
Dopamine 200mg/5ml solution for infusion ampoules

On specialist advice.

Isoprenaline
Isoprenaline hydrochloride 1mg/5ml solution for injection ampoules

On specialist advice.

Ephedrine
Ephedrine 30mg/1ml solution for injection ampoules

On specialist advice.

Ephedrine 30mg/10ml solution for injection ampoules

On specialist advice.

Ephedrine 30mg/10ml solution for injection pre-filled syringes

On specialist advice.

Metaraminol
Metaraminol 10mg/1ml solution for injection ampoules

On specialist advice.

Noradrenaline
Noradrenaline (base) 10mg/10ml solution for infusion ampoules

On specialist advice.

Noradrenaline (base) 4mg/4ml solution for infusion ampoules

On specialist advice.

Noradrenaline (base) 8mg/50ml solution for infusion pre-filled syringes

On specialist advice.

Phenylephrine
Phenylephrine 10mg/1ml solution for injection ampoules

On specialist advice.

When patients have heparin-induced thrombocytopenia type II requiring parenteral antithrombotic treatment.

Argatroban
Argatroban 50mg/50ml solution for infusion vials

See product literature or thromboprohylaxis guidelines.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

16/02/2022

East Region Formulary content agreed.

Specialist use medicines in Cardiovascular and Vascular surgery
Sodium tetradecyl sulfate
Sodium tetradecyl sulfate 0.2% solution for injection 5ml vials

On specialist advice.

Sodium tetradecyl sulfate 1% solution for injection 2ml ampoules

On specialist advice.

Aprotinin
Aprotinin 500,000 Kallikrein inactivator units/50ml solution for infusion vials

On specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

16/02/2022

East Region Formulary content agreed.

Treatment of occluded central access with antithrombotics
Urokinase
Urokinase 10,000unit powder for solution for injection vials

On specialist advice.

Alteplase
Alteplase 2mg powder for solution for injection vials

On specialist advice.

Inhibition of platelet aggregation during renal dialysis, when heparins are unsuitable or contraindicated.

Epoprostenol
Epoprostenol 500microgram powder and solvent (pH10.5) for solution for infusion vials

On specialist advice.

Epoprostenol 500microgram powder and solvent for solution for infusion vials

On specialist advice.

Epoprostenol 500microgram powder (pH12) for solution for infusion vials

On specialist advice.

Epoprostenol 1.5mg powder and solvent (pH10.5) for solution for infusion vials

On specialist advice.

Epoprostenol 1.5mg powder and solvent for solution for infusion vials

On specialist advice.

Epoprostenol 1.5mg powder (pH12) for solution for infusion vials

On specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

16/02/2022

East Region Formulary content agreed.

Specialist use medicines in percutaneous coronary intervention
Tirofiban
Tirofiban 12.5mg/250ml infusion bags

On specialist advice.

Tirofiban 12.5mg/50ml solution for infusion vials

On specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

16/02/2022

East Region Formulary content agreed.

Miscellaneous specialist use medicines in cardiology
Clonidine
Clonidine 25microgram tablets

On specialist advice.

Ajmaline
Gilurytmal 50mg/10ml solution for injection ampoules

On specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

16/02/2022

East Region Formulary content agreed.

Treatment of occluded central access with antithrombotics

Urokinase 10,000unit powder for solution for injection vials, or 25,000unit powder for solution for injection vials [Specialist Use Only].

Urokinase
Urokinase 10,000unit powder for solution for injection vials

On specialist advice.

Alteplase
Alteplase 2mg powder for solution for injection vials

On specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.
  • Preparation of alteplase 2mg is currently (May 2023) an unlicensed imported medicine.

History Notes

19/06/2023

East Region Formulary content agreed - ERFC 07/06/2023.

Prevention of clotting - IV flushes
Heparin
Heparin sodium 50units/5ml patency solution ampoules

Follow specialist advice.

Heparin sodium 200units/2ml patency solution ampoules

Follow specialist advice.

Prescribing Notes:

  • Please refer to local guidelines for further information.

History Notes

19/06/2023

East Region Formulary content agreed - ERFC 07/06/2023.